BARCELONA, Spain(AP) Barcelona lost both midfielder Andres Iniesta and forward Alexis Sanchez to injury during Wednesday's cup game against Real Madrid, paying a heavy price for its passage to the Copa del Rey semifinals.
Iniesta limped off at the half-hour mark favoring his left leg. The club said he will undergo tests Thursday to determine the recovery time from a torn muscle.
Forward Pedro Rodriguez went on and scored Barcelona's opener in the 43rd before Dani Alves quickly doubled the lead. Real Madrid scored twice to force a draw on the night but Barcelona won 4-3 on aggregate.
Alexis, who was sidelined to start the season with a leg injury, was substituted by Javier Mascherano in the 79th after injuring his shoulder and is expected to miss one to two weeks.
Barcelona plays Villarreal on Saturday in the Spanish league. It will face either Valencia or Levante in the Copa del Rey semifinals in early February.
The Spanish champions are already missing striker David Villa, midfielder Ibrahim Afellay and defender Andreu Fontas to long-term injuries.